Day :
- Drugs from Natural Sources
Session Introduction
Aizman Roman
Novosibirsk State Pedagogical University, 630126, Russia
Title: THE EFFECTS of plant rhizome Curcuma longa on carbohydrate metabolism in diabetic rats
Time : 12:15-12:50

Biography:
Aizman Roman, Head of the Dept. of Human Anatomy, Physiology and Safety of Life, Doctor of Biological Sciences, Professor, the Honorary worker of science of the Russian Federation.. Scientific director of 8 doctor's and 40 candidate's dissertations, the author and co-author of about 500 scientific and methodical works, the head of Ph.D. programs on physiology & safety of life. He has been serving as an editorial board member of 3 reputed journals and 3 dissertation councils. He has diplomas of the Ministry of Education of the Russian Federation, the Ministry on Extreme situations, the Medals «Property of Siberia».
Abstract:
The intake of the turmeric rhizomes in rats with diabetes, as compared with the same animals on a standard diet, resulted in the lower increasing of the glucose concentration in blood, the decrease of glucose absorption in the gut, higher concentration of the insulin and C-peptide in plasma and significant increase of glycogen level in the liver. The microstructure of pancreatic tissue samples of experimental animals using turmeric was characterized by the better preservation of the islet apparatus in comparison with a group of animals on a standard diet.
The results indicate the positive effect of the Curcuma longa rhizomes on the homeostatic mechanisms of the carbohydrate metabolism regulation in the alloxan-induced diabetic rats.
Mulugeta Tamene A
Federal job creation and food security Agency Solid waste management specialist Ethiopia
Title: Occupational respiratory health symptoms and associated factors among street sweepers in Addis Ababa, Ethiopia
Time : 13:50-14:30
Biography:
Mulugeta Tamene has completed his Master’s program from Africa Medical College Addis Ababa, Ethiopia in 2016. He is a solid waste management specialist in Federal job creation and food security Agency in Ethiopia.
Abstract:
Occupational hazards are becoming the major concern for public health. Occupational health awareness in Ethiopia is not well informed, especially among street sweepers. And this resulted in extensively high prevalence of occupational respiratory symptoms. Thus, this research is aiming to assess occupational respiratory health symptoms and associated factors among street sweepers in Addis Ababa. A cross-sectional study was conducted from January 2016 to march 2016 from five sub cities, and three Woredas were selected using random sampling system. Univariate analysis, logistic regression analysis was performed to select all the independent variables with 95% Confidence Interval (CI) and p < 0.05 considered to be significant. Epinfo version 3.5.1 and SPSS Version 20 used for data entry and analysis. The overall prevalence of respiratory symptoms among street sweepers was 279(68.9%). Our finding showed that respiratory symptoms including cough 180(44.4%), shortness of breath 137(33.8%), sneezing 181(55.3%), and nose irritation 134(33.1%) as well as manifestation of eye discomfort 193(47.7%) were the main ones. Respiratory symptoms were associated with Age 28-37 (AOR= 2.65 95% CI: 1.362, 5.166) and 38-47 (AOR= 2.051 95% CI: 1.018, 4.132), past history of emphysema (AOR= 2.53 95% CI: 1.072, 5.97) and TB (AOR=7.24 95% CI 1.584, 3.065). Therefore, respiratory symptoms were highly prevalent among street sweepers. Pre-employment, on job training; improving hygienic practices and proper utilization of PPE are critical steps to reduce the burden respiratory problems among the street sweeper. Moreover, the proper monitoring and periodic medical checkup may increase the health and safety of workers.
Rahul Hajare
Ministry of Health and Family Welfare, India
Title: Anti-Aging: Diversity of Indian Chickpea (Cicer Arietinum)
Time : 14:30-15:10

Biography:
Rahul Hajare is a post-doctoral student of Renowned Scientist Dr. Ramesh Paranjape, Retired Director and Scientist ‘G’ National AIDS Research Institute, India. He is affiliated to National AIDS Research Institute Pune, India. Dr.Hajare has won World Academic Championship-2017 in Pharmacy (Antiretroviral Therapy) and certified as Fellow, Directorate of Pharmacy, IASR (Lifetime Membership). He is a formerly post-doctoral fellow of Indian Council of Medical Research New Delhi. He has M.Pharm, Masters in Quality Assurance from Nagpur University. He has completed his PhD at the age of 32 years from Vinayaka Missions University.
Abstract:
According to the Oxford English Dictionary middle age is between 45 and 65. Chickpea or chick pea (Cicer arietinum) are a legume of the family Fabaceae, subfamily Faboideae. Chickpeas have high in protein and one of the earliest cultivated vegetables, 7500 years old remains have been found in the Middle East. It is the name of a fast-growing tree. Sun protection was the most commonly reported reason for applying Chick pea (type-II). Cicer arietinum extracts contain folate (B9) 43%. Folate (like pantothenic acid B5) has a λmax of 335 nm resulting in absorption of ultraviolet A radiation. When compared to titanium dioxide, folate has comparable efficacy in UVA absorption.2 In contrast to pantothenic acid B, the result of folate absorption of UVA is not mutagenic.3 Thus, the use of Chick pea powder for sun protection and to reduce wrinkle is supported by the presence of folate. Acne treatment or prevention was the second most commonly reported reason for applying Chick pea powder. Dr. Stefanie Williams reported that Chick pea powder has strong anti-inflammatory, significant antioxidant, and slight antibacterial properties.4 Thus, Chick pea may impact two of the important etiologic pathways in acne pathogenesis—inflammation and bacterial overgrowth. A study to determine the effects of Chick pea powder on Propionibacterium acnes is underway in my laboratory. Skin cooling, whitening and beautification were additional reported reasons for application of Chick pea powder. It has shown wrinkle reduction.
Rahul Hajare
ICMR- National AIDS Research Institute India
Title: Dysmenorrhea and Impact on Quality of Life to Reduce the Ability to Function Time Schedule in Pharmaceutical Institution Privately Survey in Small Town from Pune District
Time : 15:10-15:50

Biography:
Rahul Hajare is a post-doctoral student of Renowned Scientist Respected Dr. R S. Paranjape Retired Director and Scientist ‘G’ National AIDS Research Institute India. He achieved his training at the National AIDS Research Institute, the reputed and primer HIV research institute in India. Hajare is board certified by Director-in-Charge, National AIDS Research Institute, the Secretory Board of Management KLE Society Belagavi and Registrar Vinayaka Mission’s Research Foundation. Hajare won World Academic Championship-2017 in Pharmacy (Antiretroviral Therapy) and certified as Fellow, Directorate of Pharmacy, IASR (Lifetime Membership).
Abstract:
Dysmenorrhea, painful menstruation, is a common chronic condition of pain that affects a wide range of young women capable of reducing their quality of life, decrease their ability to function at a 100 percent and ultimately causing a reduction in productively for the affected person for a period of time. Many studies have shown that the level of knowledge about dysmenorrhea is unsatisfactory especially in young women and that it indeed has the ability to disrupt a peaceful flow in rhythm and pattern of women in executing daily activities, the aim of this study is therefore to determine the true extent at which dysmenorrhea interferes with daily activities. While there is considerable literature on this subject, yet, only very few of these studies were done in India and none could be found in existing literatures about dysmenorrhea and impact on quality of life to reduce the ability to function time table in pharmaceutical institution.
Saeid Parsa
Material and Energy Research Center Iran
Title: Systematic Approach to Prevent Skin Leishmania
Time : 15:50-16:30
Biography:
Material and Energy Research Center, Tehran, I.R. Iran
Abstract:
Skin Leishmania is a skin disease which is caused by the bite of sand-flies. Sand-flies are reproduced in warm and humid locations and live in remote places under home-stays. The disease is caused by Leishmania parasite. Another way to transmit the disease is from exudates. There are two types of Leishmania exudates, dry and wet, the secondary is painful and could be contagious. The objective of this paper is to plan a model to prevent sand-flies to reproduce and preventing the population from Skin Leishmania.
Batool Sadeghi-Nejad
Abadan School of Medical Sciences Iran
Title: In vitro Antileishmanial activity of Artemisia dracunculus and Heracleum persicum extracts in comparison with Glucantime
Time : 16:30-17:10

Biography:
Batool Sadeghi-Nejad Graduated of bachelor degree (B. Sc.) in the field of public health from Isfahan University of Medical Sciences on Feb. 15 1988. Holder of master degree (M. Sc.) in the field of Medical Parasitology from Isfahan University of Medical Sciences on April 30 1997. Holder Ph.D. degree in Medical Mycology from Botany department of Pune University, India on Feb. 2008. She is members of Scientist Academic Institution, Abadan School of Medical Sciences, Abadan, Iran (Assistant professor, Ph.D Medical Mycology). She has published more than 24 papers in reputed journals and has been serving as a reviewer board member of repute.
Abstract:
Background & objectives: Cutaneous leishmaniasis (CL) is one of the most common parasitic diseases. It is one of the major public health in developing countries and throughout the world. Pentavalent antimonial compounds like pentostam and glucantime has been used to treat CL for the last 50 years. The use of these compounds has some limitations such as long duration of treatment, high expenses of drugs, and methods of drug use which are intradermal and intramuscular injection. Beside these, lack of response to the treatment in 10-15% of cases and toxic effects on heart, liver, and kindneys are other possible side effects [1-3]. Hence, the objective of the present survey was to state the antileishmanial activity of two herbal medicine (Artemisia dracunculus and Heracleum persicum) extracts were evaluated against Leishmania major and Leishmania infantum using colorimetric MTT (2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2H-tetrazolium bromide) assay and compared to the glucantime as a reference. Materials and Methods: The leaves extracts of selected plants were obtained by maceration. The in vitro assays were carried out on L. major and L. infantum using colorimetric MTT assay in comparison with glucantime. The concentration-response curves tested extracts and glucantime solutions were designed and IC50 values were located. Results: Anti-Leishmina effects of A. dracunculus and H. persicum) on L. major and L. infantum promastigote were revealed with 50% inhibitory concentration (IC50) values of 49.67 and 42.23 mg ml-1 for A. dracunculus , 81.15 and 73.17 mg mg ml-1 for H. persicum. In the comparison with the standard drug, glucantime, which had IC50 value of 40.2 mg ml-1 for L.major and 18.5 mg ml-1 for L. infantum promastigote after 72 hours incubation, respectively. Conclusion: These results revealed that compounds from Satureja khuzestanica and Heracleum persicum have anti-leishmania properties that necessary to survey the effects of these extracts on leishmania genus in animal models in future.
Batool Sadeghi-Nejad
Abadan School of Medical Sciences Iran
Title: An in-vitro study of the antimicrobial efficacy of personal productive herbal- maked toothpaste on oral pathogens
Time : 17:10-17:50

Biography:
Batool Sadeghi-Nejad Graduated of bachelor degree (B. Sc.) in the field of public health from Isfahan University of Medical Sciences on Feb. 15 1988. Holder of master degree (M. Sc.) in the field of Medical Parasitology from Isfahan University of Medical Sciences on April 30 1997. Holder Ph.D. degree in Medical Mycology from Botany department of Pune University, India on Feb. 2008. She is members of Scientist Academic Institution, Abadan School of Medical Sciences, Abadan, Iran (Assistant professor, Ph.D Medical Mycology). She has published more than 24 papers in reputed journals and has been serving as a reviewer board member of repute.
Abstract:
Background & Aim: Dental plaque is an important risk factor for the development of dental and periodontal disease. In most cases tooth brushing only removes a limited amount of dental plaque and other chemical agents are required to reduce the microbial load. The purpose of this survey was to determine in vitro antimicrobial effects of herbal-made toothpaste containing the extracts of Artemisia dracunculus, Satureja khuzestanica and Myrtus communis against oral pathogens related to caries and oral fungal infections. Materials and methods: Antimicrobial effectiveness an herbal-made toothpaste was evaluated against five microorganisms: Streptococcus mutans, Lactobaccilus caseie, Streptococcus sanguis, Streptococcus salivarius and Cadida albicans by agar well diffusion method. Agar well diffusion method. The herbal- maked toothpaste was tested at four different concentrations: 1:4(25%), 1:1(50%), 3:4(75%) and full strength (100%) with sterile distilled water as the diluent. Results: After 24 hours of incubation, the maximum mean diameter of inhibition zone against tested oral pathogens by Lactobaccilus caseie (17 to 30mm), C. albicans (15-27mm) and the minimum mean diameter of inhibition zone against Streptococcus mutans (17-20mm). Conclusions: The results indicate tested herbal toothpaste was a significant product to inhibit the growth of plaque bacteria and yeast.